๐Ÿฆ  Immune Master

Advanced Nursing Education Game for Hypersensitivity & Allergic Disorders

๐Ÿ”Š

Welcome to Immune Master! ๐ŸŽฎ

This interactive game helps nursing students master hypersensitivity reactions, allergic disorders, and immune system responses. Learn to recognize patterns, understand mechanisms, and develop critical thinking skills for patient care.

๐Ÿ† Your Progress

Quiz Score: 0/12

Simulations: 0

๐Ÿ“š Learning Goals

โ€ข Master hypersensitivity types

โ€ข Recognize anaphylaxis signs

โ€ข Understand mediator actions

โšก Key Concepts

โ€ข IgE-mediated vs T-cell responses

โ€ข Immediate vs delayed reactions

โ€ข Emergency interventions

Types of Hypersensitivity Reactions ๐Ÿ”ฌ

Click on each card to learn more about different hypersensitivity mechanisms.

โšก Type I - Immediate (IgE-mediated)

Onset: Seconds to minutes
Mechanism: Mast cell degranulation
Mediators: Histamine, leukotrienes
Examples: Anaphylaxis, hay fever

๐Ÿฉธ Type II - Cytotoxic

Onset: Minutes to hours
Mechanism: Antibody-mediated
Target: Cell surface antigens
Examples: Hemolytic anemia

๐Ÿ”— Type III - Immune Complex

Onset: 3-8 hours
Mechanism: Antigen-antibody complexes
Location: Blood vessels, organs
Examples: Serum sickness

๐Ÿ• Type IV - Delayed (T-cell mediated)

Onset: 24-48 hours
Mechanism: T-cell activation
Mediators: Cytokines
Examples: Contact dermatitis, TB test

๐ŸŽฏ Clinical Pearl

Remember: Type I reactions are immediate and life-threatening (anaphylaxis), while Type IV are delayed but can cause significant tissue damage (poison ivy). Always assess onset timing!

Hypersensitivity Reaction Timeline โฐ

Visualize how different hypersensitivity reactions develop over time.

Type I (Immediate)
Type II (Cytotoxic)
Type III (Immune Complex)
Type IV (Delayed)
0 min 1 hr 8 hr 24 hr 48 hr

โš ๏ธ Critical Intervention Windows

Anaphylaxis: Immediate epinephrine
Contact dermatitis: Remove trigger, cool compresses
Monitoring: 4-8 hr rebound risk

Test Your Knowledge ๐ŸŽฏ

Loading question...

Allergic Reaction Simulator ๐Ÿ‘จโ€โš•๏ธ

Time: 00:00

Patient Information

Name: Sarah Johnson

Age: 28 years

Allergies: Penicillin, shellfish

Current Status: Stable

Scenario

Patient received IV antibiotic 15 minutes ago

Now complaining of itching and feeling "funny"

Trigger Exposure: 15 min ago

Vital Signs

88
HR (bpm)
120/80
BP (mmHg)
98
O2 Sat (%)
18
RR (breaths/min)
Patient Stable

Current Symptoms

Itching (mild)
Tingling sensation
Feeling anxious

Diagnostic Tests & Monitoring ๐Ÿงช

Explore different diagnostic approaches for hypersensitivity reactions.

Skin Testing

Allergy Testing
โ€ข Prick/scratch test for immediate reactions
โ€ข Intradermal for delayed responses
โ€ข Positive = wheal + flare reaction

Total IgE (RAST)

Serum Test
โ€ข Elevated in Type I reactions
โ€ข Confirms IgE-mediated response
โ€ข Normal: <100 IU/mL

CBC with Differential

Blood Work
โ€ข Elevated eosinophils (>4%)
โ€ข Indicates allergic activity
โ€ข Monitor for infections

Serum Tryptase

Mast Cell Marker
โ€ข Elevated in anaphylaxis
โ€ข Peak 1-2 hours post-reaction
โ€ข Confirms mast cell degranulation

Patch Testing

Contact Allergy
โ€ข For Type IV reactions
โ€ข Applied for 48 hours
โ€ข Read at 72-96 hours

Histamine Levels

Mediator Test
โ€ข Elevated in acute reactions
โ€ข Short half-life (minutes)
โ€ข Must draw immediately
Reaction Severity: MILD

Monitor for progression